Nanoparticles assessment in different environments

9-Gonzalez,2015.C-elegans as a tool for in vivo NPHow nanoparticles interact with the environment and with cells is becoming an important issue due to the increasing development of nanoscience, nanotechnology and nanomedicine. In our group, we evaluate the fate and toxicity of nanoparticles in different systems, such as cells or C. elegans, its interaction with proteins, and some medical applications of different nanostructures. Some of the publications regarding this topic are the following:

Albumin-coated SPIONs: An experimental and theoretical evaluation of protein conformation, binding affinity, and competition with serum proteins.
Siminy Yu, Alex Perálvarez-Marín, Caterina Minelli, Jordi Faraudo, Anna Roig and Anna Laromaine
Nanoscale, May 2016, Accepted Manuscript. DOI: 10.1039/C6NR01732K.

Protective effects of Bovine Serum Albumin on superparamagnetic iron oxide nanoparticles evaluated in the nematode Caenorhabditis elegans
Laura Gonzalez-Moragas, Si-Ming Yu, Elisa Carenza, Anna Laromaine*,  Anna Roig
ACS Biomater. Sci. Eng.
 2015, 1(11), 1129-1138. DOI: 10.1021/acsbiomaterials.5b00253

C-elegans as an in vivo toolkit for nanoparticles assessment  
L. Gonzalez-Moragas, A. Roig and A. Laromaine* 
Advances in Colloid and Interface Science
 2015, 219, 10-26. DOI: 10.1016/j.cis.2015.02.001

Encapsulation of VEGF165 in magnetic PLGA nanocapsules for potential local delivery and bioactivity into human brain endothelial cells 
Elisa Carenza, Olivier Jordan, Pablo San Segundo Martínez, Radovan Jiřík, Zenon Starčuk jr., Gerrit Borchard, Anna Rosell* and Anna Roig*
Journal of Materials Chemistry B 2015, 3, 12, 2538-2544. DOI: 10.1039/c4tb01895h

Enhanced stability of superparamagnetic iron oxide nanoparticles in biological media using a pH adjusted-BSA adsorption protocol
Si-Ming Yu, Anna Laromaine*, Anna Roig*
Journal of Nanoparticle Research (2014) 16:2484 DOI 10.1007/s11051-014-2484-

Rapid synthesis of water- dispersible SPIONs by microwave assisted route for safe labeling of endothelial progenitor cells
Elisa Carenza, Verónica Barceló, Anna Morancho, Joan Montaner, Anna Rosell*, Anna Roig*
Acta Biomaterialia 10 (2014) 3775–3785 DOI:10.1016/j.actbio.2014.04.010

Magnetically Decorated Multi-Walled Carbon Nanotubes as Dual MRI and SPECT/CT Contrast Agents
Julie Tzu-Wen Wang, Laura Cabana, Maxime Bourgognon, Houmam Kafa, Andrea Protti, Kerrie Venner, Ajay M. Shah, Jane Sosabowski, Stephen J. Mather, Anna Roig, Xiaoxing Ke, Gustaaf Van Tendeloo, Rafael T.M.deRosales, Gerard Tobias,* Khuloud T. Al-Jamal*
Advanced Functional Materials 24 (2014) 1880–1894 DOI:10.1002/adfm.201302892

In vitro Angiogenic Performance and in vivo Brain Targeting of Magnetized Endothelial Progenitor Cells for Neurorepair Therapies
Elisa Carenza, Verónica Barceló, Anna Morancho, Lisa Levander, Cristina Boada, Anna Laromaine, Anna Roig*, Joan Montaner, Anna Rosell*
Nanomedicine: NBM 10, 1 (2014) 225-234 DOI:10.1016/j.nano.2013.06.005

Preparation and characterization of iron containing liposomes: their effect on iron uptake by Caco-2 cells
Laura Hermida, Anna Roig, Carlos Bregni, Manuel Sabés-Xamaní, Ramon Barnadas*
Journal of Liposome Research 21 3 (2011) 203-212 DOI: 10.3109/08982104.2010.517536

Paper-Supported Three-Dimensional Cell Culture for Tissue-Based Bioassays,
R.Derda, A.Laromaine, A.Mamoto, S.Tang, T.Mammoto, D.Ingber, G.M.Whitesides.
Proceedings Natural Academy Sciences 2010, 106, 44, 18457. Highlighted in Nature Methods 2009,6,12,865.